Bus Palermo to Rome - Compare all Companies

Latest reviews for bus companies on the route Palermo - Rome

Noemi, 9/4/2025

Viaggio con Salemi autobus da diversi mesi, circa una volta al mese, e mi trovo sempre benissimo! 🚍✨ I pullman sono comodi e puntuali, dotati di televisione e di un bagno sempre perfettamente funzion ... Viaggio con Salemi autobus da diversi mesi, circa una volta al mese, e mi trovo sempre benissimo! 🚍✨ I pullman sono comodi e puntuali, dotati di televisione e di un bagno sempre perfettamente funzionante: pulito, con carta igienica, sapone e specchio pronti all’uso (cosa non scontata nei viaggi lunghi, e che con Salemi non mi è mai mancata!). Salemi è stato l’ultimo autobus che ho provato, prima viaggiavo con Flixbus o Itabus, ma non c’è paragone, infatti sono viaggiatrice fissa con voi. Non ho mai trovato il bagno inagibile, sempre tutto curato nei minimi dettagli. Un punto di forza incredibile sono gli autisti: simpatici, cordiali e professionali, riescono a rendere il viaggio non solo confortevole ma anche piacevole. Offrono anche una bottiglia d’acqua di benvenuto ogni volta. Un servizio davvero affidabile e impeccabile, per me ormai una garanzia. Complimenti a tutto lo staff Salemi, continuate così! 👏😊

All bus stations and stops in Palermo and Rome

In the map below, you can see where to find all bus stations in Palermo and Rome.

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Rome? Compare all modes of transports from Palermo to Rome.

Service and Comfort on the bus from Palermo to Rome

Want to know which seat classes are available on the buses from Palermo to Rome? Or which bus companies serve the route Palermo to Rome? Below you will find answers to your questions.

FAQs about the Palermo to Rome bus

How much does a Palermo Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from and takes to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Palermo to Rome?

This route is offered by companies with a range of ticket prices between and . Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Palermo to Rome each day?

Every day, the Palermo to Rome bus route is served by approximately connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Rome take?

The fastest bus from Palermo to Rome is offered by and takes . Bus tickets for this connection cost . In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Rome?

The earliest bus arriving in Rome from Palermo starts at . However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Rome?

The latest bus trip departing from Palermo for Rome starts at . Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Rome route?

When traveling by bus from Palermo to Rome, passengers can travel with . With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Rome?

You can check all the direct connections between Palermo and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: .

What can I take with me on the Palermo to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Palermo to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for daily trips between Palermo and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Palermo to Rome?

Prices and availability for trips between Palermo and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

More bus routes to Palermo and to Rome

Here’s an overview of the most popular bus routes to Palermo and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!